Pedro Pais

(PhD Student) *

Alternative Pages: Google Scholar; Research ID; iBB webpage

Status at iBB - Institute for Bioengineering and Biosciences:

·         Researcher of the Biological Sciences Research Group

Education:

  • Graduation in Cell and Molecular Biology, Faculty of Sciences and Technology, New University of Lisbon, Portugal, 2012

  • Master in Biotechnology, Instituto Superior Técnico, University of Lisbon, Portugal, 2014

Positions:

  • PhD Student in Biotechnology, under the supervision of Professor Miguel Cacho Teixeira.

Research Activities:

  • Mechanisms of antifungal drug resistance in the human pathogen Candida glabrata

  • Microbial physiology and molecular biology

  • Chemogenomics and expression proteomics.

Grants:

  • PhD scholarship PD/BD/113631/2015, within the scope of the FCT-PhD doctoral program BIOTECnico

Publications:

Book chapters

Cavalheiro M., Costa C., Pais P., Teixeira M.C., Acquisition of resistance to azole antifungal drugs in Candida species: imidazoles versus triazoles, In: Advances in Medicine and Biology (Leon V. Berhardt, Ed.), Nova Science Publishers, Inc., NY, USA, vol.8, chapter 9, 2016

Costa C., Pais P., Teixeira M.C., "Multidrug resistance in pathogenic yeasts: emphasis on the role of ABC and MFS multidrug transporters", In: The Battle Against Microbial Pathogens: Basic Science, Technological Advances and Educational Programs (A. Méndez-Vilas, Ed.), Formatex, Badajoz, Spain, p. 947-954, 2015.

Papers in International Journals

Monteiro, P.T., Pais, P., Costa, C., Manna, S., Sá-Correia, I., Teixeira, M.C., "The PathoYeastract database: an information system for the analysis of gene and genomic transcription regulation in pathogenic yeasts", Nucleic Acids Research, 45(D1):D597-D603, 2017.

Santos, R., Costa, C., Mil-Homens, D., Romão, D., de Carvalho, C.C.R., Pais, P., Mira, N.P., Fialho, A.M., Teixeira, M.C.,  The multidrug resistance transporters CgTpo1_1 and CgTpo1_2 play a role in virulence and biofilm formation in the human pathogen Candida glabrata", Cellular Microbiology, doi: 10.1111/cmi.12686.

Pais, P., Pires, C., Costa, C., Okamoto, M., Chibana, H., Teixeira, M.C., “Membrane proteomics analysis of the Candida glabrata response to 5-flucytosine: unveiling the role and regulation of the drug efflux transporters CgFlr1 and CgFlr2”, Frontiers in Microbiology, 7:2045, 2016.

Pais, P., Costa, C., Cavalheiro, M., Romão, D., Teixeira, M.C., "Transcriptional control of drug resistance, virulence and immune system evasion in pathogenic fungi: a cross-species comparison", Frontiers in Cellular and Infection Microbiology, 6: 131, 2016.

Pais, P., Costa, C., Pires, C., Shimizu, K., Chibana, H., Teixeira, M.C., “Membrane proteome-wide response to the antifungal drug clotrimazole in Candida glabrata: role of the transcription factor CgPdr1 and the Drug:H+ Antiporters CgTpo1_1 and CgTpo1_2”, Molecular and Cellular Proteomics, 15(1):57-72, 2016.

Costa, C., Ponte, A., Pais, P., Santos, R., Cavalheiro, M., Takashi, Y., Chibana, H., Teixeira, M.C., "New mechanisms of flucytosine resistance in C. glabrata unveiled by a chemogenomics analysis in S. cerevisiae", PLoS ONE, 10(8):e0135110, 2015.